Printable A-CURE 2018 Agenda
(Click to print. subject to change)

November 8, 2018

6:00 - 9:00 PM


The Art Institute of Chicago,

The Chicago Stock Exchange Trading Room

230 S. Columbus Dr.


6:00 PM

Cocktail Reception: The Chicago Stock Exchange Room, Art Institute of Chicago

7:00 - 9:00 PM


Open gallery viewing at the Art Institute to follow dinner

November, 9 2018, 8:00 AM - 4:30 PM


Meeting Site:
The Blackstone Hotel
636 South Michigan Ave.
Chicago, IL 60605

7:00 - 8:00 AM


8:00 - 8:10 AM

Welcome and Introductory Comments

SESSION I: Advances in the Basic and Preclinical Science of Acute Unloading and Myocardial Salvage

8:10 - 9:55 AM

Discussion Leaders: Nir Uriel, Ryan Tedford, Roger Hajjar

8:10 - 8:25 AM

Dan Burkhoff (Columbia),  The State of the Field: Our Current Understanding of Ventricular Unloading

8:25 - 8:40 AM

Kiyotake Ishikawa (Mt. Sinai), Cardiac Uptake and Release of Exosomes During Altered Left Ventricular Load in Ischemic HF

8:40 - 8:55 AM

Lija Swain (Tufts Medical Center), Acute Unloading and Gene Mitochondrial and Ca2+ Gene Regulation

8:55 - 9:10 AM

Kenji Sunagawa (Kyushu University), Automated Complete Cardiac Unloading and Limiting Infarct Scar Size: Exploration and Development of First Generation Autopilot System

9:10 - 9:25 AM

Jacob Möller (Odense University), Mechanical Circulatory Support by VA ECMO or Impella CP and Impact on Left Ventricular Unloading and End Organ Perfusion in a Porcine Model of Profound Cardiogenic Shock

9:25 - 9:40 AM

Carlos Santos-Gallego (Mt. Sinai), Winner: Best in Research Award, Left Ventricular Unloading with Impella Causes Cardiac Metabolic Remodeling with a Significant Reduction in Myocardial Glucose Consumption and Lactate Production

9:40 - 9:55 AM

Shiva Annamalai, (Tufts), Winner: Young Investigator Scholarship, Primary Left Ventricular Unloading Enhances Collateral Blood Flow and Reduces Infarct Size: A Preclinical Proof of Concept Study

9:55 - 10:10 AM


10:10 - 11:00 AM

Poster Session I

11:00 - 11:45 PM


James Udelson, MD

Tufts Medical Center

Chief, Division of Cardiology

Associate Editor: Circulation

Left Ventricular Remodeling:  Therapeutics Effects, Implications for Trials and Lessons from Chronic Heart Failure


11:45 - 12:50 PM


Art Hall, The Blackstone Hotel

SESSION II: Clinical Research Programs of Cardiac Unloading

12:50 - 2:10 PM

Discussion Leaders: Bart Meyns, Hermann Reichenspurner

12:50 - 1:10 PM

Ralf Westenfeld (University of Düsseldorf), The Cardio-renal System: Acute Kidney Injury and MCS, Opportunity for Improved Patient Outcomes

1:10 - 1:25 PM

Xiaoying Qiao (Tufts Medical Center); VA-ECMO Increases Urinary Levels of the Biomarker Kidney Injury Marker-1 (KIM-1) in a Preclinical Model of Acute Myocardial Infarction

1:25 - 1:40 PM

Julian Wiora (University of Düsseldorf), Impella Is Associated With Reduced Incidence Of Contrast-Induced Nephropathy In Patients At Higher Risk For PCI

1:40 - 1:55 PM

Andreas Schäfer (Hannover Medical School), Impact of Unloading During AMI-CGS: The Hannover Cardiac Unloading Registry (HACURE) and European Multicenter Experience.

1:55 - 2:10 PM

Alexander Bernhardt (University Hospital Hamburg-Eppendorf), First In Man Implantations of a Newly Designed Transaortic Axial Flow Ventricular Assist Device, Impella 5.5

2:10 - 3:00 PM

Poster Session II

SESSION III: New Frontiers and Clinical Translation of Unloading

3:00 - 4:25 PM

Discussion Leaders: Mark Anderson, Michel Ovize, Carsten Tschöpe

3:00 - 3:15 PM

Ajar Kochar (Duke Clinical Research Institute), Development of Heart Failure Among Survivors of STEMI and NSTEMI and Long-term Outcomes

3:15 - 3:30 PM

Robert Kloner, MD, PhD (Chief Science Officer: Huntington Medical Research Institute & Prof. of Medicine (Clinical Scholar): University of Southern California), Survival, Differentiation and Contractility of Immature Cardiac Cells Implanted into the Outer Walls of Aorta and Vena Cavae of Rats: A Potential Step in the Development of an Auxillary Circulatory Pump

3:30 - 3:45 PM

Navin Kapur (Tufts Medical Center), Learning from the Door To Unload in STEMI Trial, Mechanical Left Ventricular Unloading as a Platform for Additional Cardioprotective Therapies

3:45 - 4:00 PM

Haroon Faraz (Hackensack University Medical Center)Case report from the Door To Unload in STEMI Study

4:00 - 4:25 PM

Panel Discussion: Designing and Executing a Pivotal DTU Clinical Trial, Dan Burkhoff, Mark Anderson, Navin Kapur, Haroon Faraz, Jeff Moses, Robert Kloner, Michel Ovize, Carsten Tschöpe

4:30 PM

Closing Comments, Audience Feedback, and Adjourn

Cocktail Reception

The Barbershop and 1600 Club
The Blackstone Hotel
5:00 - 7:00 PM