August 29, 2019

A-CURE Cocktail and Dinner Reception

Pavilion Cambon Capucines, Paris
46 rue Cambon - 75001 Paris

6:00 PM

Cocktail Reception


7:00 PM


August 30, 2019

Meeting Site

InterContinental Paris le Grand
Plenum Opera Ballroom
2 Rue Scribe
Paris, 75009, France

7:00-8:00 AM


8:10 – 10:00 AM

Session I

Advances in Basic and Preclinical Science of Acute Unloading and Myocardial Salvage

Discussion leaders: Ralf Westenfeld, Kenji Sunagawa


8:10 – 8:25

Dan Burkhoff (Columbia), The State of the Field of Unloading

8:25 – 8:40

Howard Chen (Tufts Medical Center), A Novel Imaging Probe for the Detection of Autophagy in Preclinical Swine Models of Myocardial Ischemia-Reperfusion Injury

8:40 – 8:55

Lija Swain (Tufts Medical Center), Acute Unloading Preserves Energy Substrate Utilization and Protects the Functional Integrity of Mitochondrial Complex I in Preclinical Models of Ischemia without Reperfusion

8:55 – 9:10

Nanna Udesen (Odense University Hospital), Winner: Young Investigator Scholarship, Impact of Concomitant Vasoactive Treatment in Active Left Ventricular Unloading in Cardiogenic Shock

9:10 – 9:25


9:25 – 9:40

Kiyotake Ishikawa (Mt. Sinai Hospital), Improving the Gene Transduction Efficiency of Intracoronary Delivery Using the Impella

9:40 – 9:55

Heimo Ehmke (University Center Hamburg-Eppendorf), Winner: Best in Research Award, Reversal of Myocardial Infarction-induced Changes in Gene Expression by Ventricular Unloading in Rats

9:55 – 10:10

Dan Burkhoff (Columbia University) A Novel Superior Vena Cava Occlusion Catheter System Reduces Biventricular Filling Pressures While Maintaining Cardiac Output in a Model of Acute Congestive Heart Failure

10:10 – 11:00 AM

Poster Session #1

11:00 – 11:45 AM

Keynote Speaker

Introduction: Dan Burkhoff
Douglas Mann, MD
Washington University School of Medicine in St. Louis
The Role of Hemodynamic Load in Left Ventricular Remodeling and Reverse Left Ventricular Remodeling


11:45 – 12:15 PM

Panel Discussion: Recovering the Failing Heart: What’s the best approach?
Douglas Mann, Rob Dowling, Navin Kapur, Dan Burkhoff, Ryan Tedford, Jacob Møller

Moderator: Bart Meyns

12:15 – 1:00 PM


1:00-2:00 PM

Poster Session #2

2:00 – 4:30 PM

Session II

New Frontiers and Clinical Translation of Cardiac Unloading

Discussion leaders: Claudius Mahr, Andreas Schäfer

2:00 - 2:15

L. Christian Napp (Hannover Medical School), Impella Mechanical Circulatory Support for Takotsubo Syndrome with Shock

2:15 - 2:30

Navin Kapur (Tufts Medical Center), Cardiorenal Implications of Acute Mechanical Circulatory Support

2:30 - 2:45

Bernard Schieffer (University Hospital Giessen and Marburg), Impact of Microaxillar Mechanical Ventricular Support on Renal Resistive Index in Patients with Cardiogenic Shock After Myocardial Infarction

2:45 - 3:00

Carsten Tschöpe (Charite, CVK) Prolonged Impella – Mode of Action and Clinical Implications

3:00 - 3:15

Alexander Bernhardt (University Hospital Hamburg-Eppendorf) Long-term Support Using Surgically Implanted Impella Devices

3:15 - 3:30


Discussion leaders: Patrick Hunziker, George Vetrovec

3:30 - 3:45

Bill O’Neill (Henry Ford Hospital), Update from the National Cardiogenic Shock Initiative

3:45 - 4:00

Jason Williams (Ocean Springs Hospital), Peri-procedural Ventricular Unloading with Impella Optimizes Outcomes in High-risk Patients at a Community Hospital

4:00 - 4:15

Jaime Hernandez-Montfort (UTMB Health), Longitudinal Impact of Temporary Mechanical Circulatory Support on Durable Ventricular Assist Device Outcomes: An IMACS Registry Analysis

4:15 - 4:30

Bart Meyns (KU Leuven), How to Unload the Heart on ECMO

4:30 PM

Closing Comments, Audience Feedback, and Adjourn

4:30 – 4:45

Navin Kapur (Tuft Medical Center), DTU Clinical Trial Update

5:00-7:00 PM

Cocktail Reception & Poster Viewing Salon Ravel