August 29, 2019
A-CURE Cocktail and Dinner Reception
Pavilion Cambon Capucines, Paris
46 rue Cambon - 75001 Paris
6:00 PM
Cocktail Reception
7:00 PM
Dinner
August 30, 2019
Meeting Site
InterContinental Paris le Grand
Plenum Opera Ballroom
2 Rue Scribe
Paris, 75009, France
7:00-8:00 AM
BREAKFAST: BERLIOZ ROOM
8:10 – 10:00 AM
Session I
Advances in Basic and Preclinical Science of Acute Unloading and Myocardial Salvage
Discussion leaders: Ralf Westenfeld, Kenji Sunagawa
8:10 – 8:25
Dan Burkhoff (Columbia), The State of the Field of Unloading
8:25 – 8:40
Howard Chen (Tufts Medical Center), A Novel Imaging Probe for the Detection of Autophagy in Preclinical Swine Models of Myocardial Ischemia-Reperfusion Injury
8:40 – 8:55
Lija Swain (Tufts Medical Center), Acute Unloading Preserves Energy Substrate Utilization and Protects the Functional Integrity of Mitochondrial Complex I in Preclinical Models of Ischemia without Reperfusion
8:55 – 9:10
Nanna Udesen (Odense University Hospital), Winner: Young Investigator Scholarship, Impact of Concomitant Vasoactive Treatment in Active Left Ventricular Unloading in Cardiogenic Shock
9:10 – 9:25
Break
9:25 – 9:40
Kiyotake Ishikawa (Mt. Sinai Hospital), Improving the Gene Transduction Efficiency of Intracoronary Delivery Using the Impella
9:40 – 9:55
Heimo Ehmke (University Center Hamburg-Eppendorf), Winner: Best in Research Award, Reversal of Myocardial Infarction-induced Changes in Gene Expression by Ventricular Unloading in Rats
9:55 – 10:10
Dan Burkhoff (Columbia University) A Novel Superior Vena Cava Occlusion Catheter System Reduces Biventricular Filling Pressures While Maintaining Cardiac Output in a Model of Acute Congestive Heart Failure
10:10 – 11:00 AM
Poster Session #1
11:00 – 11:45 AM
Keynote Speaker
Introduction: Dan Burkhoff
Douglas Mann, MD
Washington University School of Medicine in St. Louis
The Role of Hemodynamic Load in Left Ventricular Remodeling and Reverse Left Ventricular Remodeling
11:45 – 12:15 PM
Panel Discussion: Recovering the Failing Heart: What’s the best approach?
Douglas Mann, Rob Dowling, Navin Kapur, Dan Burkhoff, Ryan Tedford, Jacob Møller
Moderator: Bart Meyns
12:15 – 1:00 PM
LUNCH: BERLIOZ ROOM
1:00-2:00 PM
Poster Session #2
2:00 – 4:30 PM
Session II
New Frontiers and Clinical Translation of Cardiac Unloading
Discussion leaders: Claudius Mahr, Andreas Schäfer
2:00 - 2:15
L. Christian Napp (Hannover Medical School), Impella Mechanical Circulatory Support for Takotsubo Syndrome with Shock
2:15 - 2:30
Navin Kapur (Tufts Medical Center), Cardiorenal Implications of Acute Mechanical Circulatory Support
2:30 - 2:45
Bernard Schieffer (University Hospital Giessen and Marburg), Impact of Microaxillar Mechanical Ventricular Support on Renal Resistive Index in Patients with Cardiogenic Shock After Myocardial Infarction
2:45 - 3:00
Carsten Tschöpe (Charite, CVK) Prolonged Impella – Mode of Action and Clinical Implications
3:00 - 3:15
Alexander Bernhardt (University Hospital Hamburg-Eppendorf) Long-term Support Using Surgically Implanted Impella Devices
3:15 - 3:30
Break
Discussion leaders: Patrick Hunziker, George Vetrovec
3:30 - 3:45
Bill O’Neill (Henry Ford Hospital), Update from the National Cardiogenic Shock Initiative
3:45 - 4:00
Jason Williams (Ocean Springs Hospital), Peri-procedural Ventricular Unloading with Impella Optimizes Outcomes in High-risk Patients at a Community Hospital
4:00 - 4:15
Jaime Hernandez-Montfort (UTMB Health), Longitudinal Impact of Temporary Mechanical Circulatory Support on Durable Ventricular Assist Device Outcomes: An IMACS Registry Analysis
4:15 - 4:30
Bart Meyns (KU Leuven), How to Unload the Heart on ECMO
4:30 PM
Closing Comments, Audience Feedback, and Adjourn
4:30 – 4:45
Navin Kapur (Tuft Medical Center), DTU Clinical Trial Update
5:00-7:00 PM
Cocktail Reception & Poster Viewing Salon Ravel