August 23, 2023

Hilton Amsterdam Garden Terrace

Apollolaan 138, 1077 BG
Amsterdam, Netherlands

6:00 p.m.

Welcome Dinner & Networking Event

Cocktail Reception: 6:00 p.m.
Dinner: 7:00 p.m.
Pre-Conference Poster Session: 6:00 p.m.

RSVP only by registration or by emailing info@a-cure.org

August 24, 2023

Hilton Amsterdam

In-person:
Apollolaan 138, 1077 BG
Amsterdam, Netherlands

Virtual: Access link will be provided to registered attendees via email
All meeting times are Central European Time (CET), (GMT+1)

6:30-7:30 a.m.

Breakfast & Check-in

Check-in & Breakfast Location: Nassau & Staten Room
Symposium Location: Balzaar Ball Room

Session I

Advances in the Science of Cardiac Unloading and Myocardial Recovery

8:00-9:40 a.m.

Discussion Leaders: Claudius Mahr, DO (Medical City Heart Hospital, USA) and Dr. Med. L. Christian Napp (Hannover Medical School, Germany)

8:00 a.m.

MC: George Vetrovec, MD (Virginia Commonwealth University, USA)

Welcome and Introductory Comments

8:05-8:15 a.m.

Dan Burkhoff, MD, PhD (Cardiovascular Research Foundation, USA)

The State of the Field of Unloading: Annual Update

8:15-8:30 a.m.

Gaurav Gulati, MD (Tufts Medical Center, USA)

Right Heart Ventriculo-Vascular Coupling in Cardiac Unloading

8:30-8:45 a.m.

Hidetaka Morita, MD (NCVC Osaka, Japan)

Abstract Selected: Automated IMpella Optimized Unloading System (AIMOUS) of Impella 5.5 Precisely Controls Left Ventricular Pressure in Goat

8:45-9:00 a.m.

Rohit Ramchandra, PhD (University of Auckland, New Zealand)

Abstract Selected:Mechanical Circulatory Support using the Impella CP Reduces Directly Recorded Renal Sympathetic Nerve Activity in Cardiogenic Shock

9:00-9:10 a.m.

Open Floor Discussion

9:10-9:40 a.m.

Debate #1
Topic: Unloading and venting VA- ECMO CGS Patients: LAVA or EcPella?

Moderators:
Prof. Dr. Med. Patrick Hunziker (University Hospital Basel, Switzerland) and Nir Uriel, MD (Colmbia University Irving Medical Center, USA)

Debaters:
Bill O’Neill, MD (Henry Ford Hospital, USA) LAVA
Prof. Dr. Med. Dirk Westermann (Universitäts-Herzzentrum Freiburg, Germany) EcPella

Session II

Mechanical Preload Reduction

10:00-11:00 a.m.

Pecha Kucha Format (20 images, each 20 seconds, timed for 7 minutes each)

10:00-10:45 a.m.

Pecha Kucha
Question: Can mechanical preload reduction benefit patients?

Moderators:
Navin Kapur, MD (Tufts Medical Center, USA)
Dan Burkhoff, MD, PhD (Cardiovascular Research Foundation, USA)

Panelists:
Arvind Bhimaraj, MD (Houston Methodist Hospital, USA) Principles of Preload Reduction and Pathophysiology
Manreet Kanwar, MD (Allegheny General Hospital, USA) Acute Decompensated HF and Chronic HF
Rayan Yousefzai, MD (Houston Method Hospital, USA) PreCardia and Renal Unloading
Harrison Farber, MD (Tufts Medical Center, USA) Acute Right Heart Failure and Pulmonary Hypertension
Navin Kapur, MD (Tufts Medical Center, USA) PrePella

10:45-11:00 a.m.

Open Floor Discussion

Live Poster Session
11:00-12:00 p.m.
Diamond Room

12:00-1:00 p.m.

Lunch & Networking
Nassau & Staten Room

Session III

Clinical Evidence and Strategies for Cardiac Unloading and Recovery

1:00-3:00 p.m.

Discussion leaders: Jeff Moses, MD (Columbia University, USA) and Prof. Dr. Med. Jacob Møller (Copenhagen University Hospital, Denmark)

1:00-1:20 p.m.

Ryan Tedford, MD (Medical University South Carolina, USA)

Right Heart Failure: Evaluation and Management

1:20-1:35 p.m.

Allan Böhm, MD (National Cardiovascular Institute, Slovakia)

STOP SHOCK: Artificial Intelligence Model for Prediction of Cardiogenic Shock and MCS use

1:35-1:50 p.m.

Kanika Mody, MD (Hackensack Medical Center, USA)

Abstract Selected:GDMT Optimization in Impella 5.5 Patients

1:50-2:05 p.m.

Debbie Rinde-Hoffman, MD (Tampa General Hospital, USA)

MCS use in High-risk Non-cardiac Surgery, Bariatric Surgery and Beyond

2:05-2:20 p.m.

Thorsten Siess, PhD (Abiomed, GmbH)

The Pediatric Impella Pump

2:20-2:30 p.m.

Open floor Discussion

2:30-3:00 p.m.

Debate #2
Topic: Unloading as a Bridge to Transplant or Target for Recovery: Which Patients and Why?

Moderators:
Mark Anderson, MD (Hackensack Meridian Hospital, USA)
Prof. Dr. Med. Andreas Schäfer (Hannover Medical School, Germany)

Debaters:
Prof. Dr. Med. Alex Bernhardt (University Heart Center Hamburg, Germany) Bridge to Transplant
Jane Wilcox, MD (Northwestern University, USA) Bridge to Recovery

Session IV

Innovations in the Space: Abstract Selected Talks

3:15-5:05 p.m.

Discussion leaders: Prof. Dr. Med. Bart Meyns (KU Leuven, Belgium) and Kiyotake Ishikawa, MD, PhD (Mount Sinai, USA)

3:15-3:40 p.m.

Special Lecture
Kenji Sunagawa, MD, PhD (Kyushu Univ, Japan)

From Past Insights to Future Breakthroughs: Digital Twins to Empower PVR, Circulatory Equilibrium, and MCS

3:40-3:55 p.m.

Best in Research Award
Elric Zweck, MD, PhD (Heinrich-Heine University, Düsseldorf, Germany)

Abstract Selected:Clinical Trajectories and Outcomes in Cardiogenic Shock Phenotypes

3:55-4:10 p.m.

Young Investigator Award
Kimberly Lamberti (MIT, USA)

Abstract Selected:Pulmonary Vascular Dynamics Determines Right Heart Tolerance of Left Ventricular Mechanical Support

4:10-4:25 p.m.

Takaaki Toyofuku, MD (Saiseikai Kumamoto Hospital, Japan)

Abstract Selected:Impact of ECPELLA Support on Intermediate-term Mortality and Myocardial Protection in Patients with Refractory Cardiogenic Shock due to Acute Coronary Syndrome

4:25-4:40 p.m.

Michele Esposito, MD (Medical University of South Carolina, USA)

Abstract Selected:Acute Limb Ischemia Doubles In-Hospital Mortality Among Patients with Cardiogenic Shock: An Analysis from the Cardiogenic Shock Working Group

4:40-4:55 p.m.

Navin Kapur, MD (Tufts Medical Center, USA)*

Abstract Selected:Machine Learning Mortality Prediction for Patients with Cardiogenic Shock due to Acute Decompensated Heart Failure

*On behalf of Song Li, MD (Medical City Heart Hospital, USA)

4:55-5:05 p.m.

Open floor Discussion

5:05 p.m.

Closing Comments, Audience Feedback, and Adjourn

Symposium Survey

5:10-7:00 p.m.

Cocktail Reception & Poster Viewing
Location: Diamond Room