past Events
2018
Highlights from the 3rd Annual A-CURE Symposium
November 8-9, 2018 | Blackstone Hotel | Chicago, IL, USA
2018
Highlights from the 3rd Annual A-CURE Symposium
November 8-9, 2018 | Blackstone Hotel | Chicago, IL, USA
November 8, 2018
6:00 PM – 9:00 PM
A-CURE COCKTAIL AND DINNER RECEPTION
The Art Institute of Chicago,
The Chicago Stock Exchange Trading Room
230 S. Columbus Dr.
6:00 PM
Cocktail Reception: The Chicago Stock Exchange Room, Art Institute of Chicago
7:00 PM – 9:00 PM
Dinner Open gallery viewing at the Art Institute to follow dinner
November 9, 2018
Meeting Site
The Blackstone Hotel 636 South Michigan Ave. Chicago, IL 60605
7:00 AM – 8:00 AM
Breakfast
8:00 AM – 8:10 AM
Welcome and Introductory Comments
Session I
Topic: Advances in the Basic and Preclinical Science of
Acute Unloading and Myocardial Salvage
8:10 AM – 9:55 AM
Discussion Leaders: Nir Uriel, Ryan Tedford, Roger Hajjar
8:10 AM – 8:25 AM
Dan Burkhoff (Columbia)
Topic: The State of the Field: Our Current Understanding of Ventricular Unloading
8:25 AM – 8:40 AM
Kiyotake Ishikawa (Mt. Sinai)
Topic: Cardiac Uptake and Release of Exosomes During Altered Left Ventricular Load in Ischemic HF
8:40 AM – 8:55 AM
Lija Swain (Tufts Medical Center)
Topic: Acute Unloading and Gene Mitochondrial and Ca2+ Gene Regulation
8:55 AM – 9:10 AM
Kenji Sunagawa (Kyushu University)
Topic: Automated Complete Cardiac Unloading and Limiting Infarct Scar Size: Exploration and Development of First Generation Autopilot System
9:10 AM – 9:25 AM
Jacob Möller (Odense University)
Topic: Mechanical Circulatory Support by VA ECMO or Impella CP and Impact on Left Ventricular Unloading and End Organ Perfusion in a Porcine Model of Profound Cardiogenic Shock
9:25 AM – 9:40 AM
Carlos Santos-Gallego (Mt. Sinai)
Topic: Winner: Best in Research Award, Left Ventricular Unloading with Impella Causes Cardiac Metabolic Remodeling with a Significant Reduction in Myocardial Glucose Consumption and Lactate Production
9:40 AM – 9:55 AM
Shiva Annamalai, (Tufts)
Winner: Young Investigator Scholarship, Primary Left Ventricular Unloading Enhances Collateral Blood Flow and Reduces Infarct Size: A Preclinical Proof of Concept Study
9:55 AM – 10:10 AM
BREAK
10:10 AM – 11:00 AM
Poster Session I
11:00 AM – 11:45 AM
KEYNOTE SPEAKER
James Udelson, MD
Tufts Medical Center
Chief, Division of Cardiology
Associate Editor: Circulation
Left Ventricular Remodeling: Therapeutics Effects, Implications for Trials and Lessons from Chronic Heart Failure
11:45 AM – 12:50 PM
LUNCH: Art Hall, The Blackstone Hotel
Session II
Clinical Research Programs of Cardiac Unloading
12:50 PM – 2:10 PM
Discussion Leaders: Bart Meyns, Hermann Reichenspurner
12:50 PM – 1:10 PM
Ralf Westenfeld (University of Düsseldorf)
Topic: The Cardio-renal System: Acute Kidney Injury and MCS, Opportunity for Improved Patient Outcomes
1:10 PM – 1:25 PM
Xiaoying Qiao (Tufts Medical Center)
Topic: VA-ECMO Increases Urinary Levels of the Biomarker Kidney Injury Marker-1 (KIM-1) in a Preclinical Model of Acute Myocardial Infarction
1:25 PM – 1:40 PM
Julian Wiora (University of Düsseldorf)
Topic: Impella Is Associated With Reduced Incidence Of Contrast-Induced Nephropathy In Patients At Higher Risk For PCI
1:40 PM – 1:55 PM
Andreas Schäfer (Hannover Medical School)
Impact of Unloading During AMI-CGS: The Hannover Cardiac Unloading Registry (HACURE) and European Multicenter Experience
1:55 PM – 2:10 PM
Alexander Bernhardt (University Hospital Hamburg-Eppendorf)
Topic: First In Man Implantations of a Newly Designed Transaortic Axial Flow Ventricular Assist Device, Impella 5.5
2:10 PM – 3:00 PM
Poster Session II
Session III
New Frontiers and Clinical Translation of Unloading
3:00 PM – 4:25 PM
Discussion Leaders: Mark Anderson, Michel Ovize, Carsten Tschöpe
3:00 PM – 3:15 PM
Ajar Kochar (Duke Clinical Research Institute)
Topic: Development of Heart Failure Among Survivors of STEMI and NSTEMI and Long-term Outcomes
3:15 PM – 3:30 PM
Robert Kloner, MD, PhD (Chief Science Officer: Huntington Medical Research Institute & Prof. of Medicine (Clinical Scholar): University of Southern California)
Topic: Survival, Differentiation and Contractility of Immature Cardiac Cells Implanted into the Outer Walls of Aorta and Vena Cavae of Rats: A Potential Step in the Development of an Auxillary Circulatory Pump
3:30 PM – 3:45 PM
Navin Kapur (Tufts Medical Center)
Topic: Learning from the Door To Unload in STEMI Trial, Mechanical Left Ventricular Unloading as a Platform for Additional Cardioprotective Therapies
3:45 PM – 4:00 PM
Haroon Faraz (Hackensack University Medical Center)
Topic: Case report from the Door To Unload in STEMI Study
4:00 PM – 4:25 PM
Panel Discussion: Designing and Executing a Pivotal DTU Clinical Trial
Dan Burkhoff, Mark Anderson, Navin Kapur, Haroon Faraz, Jeff Moses, Robert Kloner, Michel Ovize, Carsten Tschöpe
4:30 PM
Closing Comments, Audience Feedback, and Adjourn
Cocktail Reception
The Barbershop and 1600 Club The Blackstone Hotel
5:00 PM – 7:00 PM
Gallery
Event Photos
Poster Gallery