past Events
2023
Highlights from the 8th Annual A-CURE Symposium
August 23-24, 2023 | Hilton Amsterdam | Amsterdam, NL
2023
Highlights from the 8th Annual A-CURE Symposium
August 23-24, 2023 | Hilton Amsterdam | Amsterdam, NL
August 23, 2023
Hilton Amsterdam Garden Terrace
Apollolaan 138, 1077 BG
Amsterdam, Netherlands
6:00 p.m.
Welcome Dinner & Networking Event
Cocktail Reception: 6:00 p.m.
Dinner: 7:00 p.m.
Pre-Conference Poster Session: 6:00 p.m.
RSVP only by registration or by emailing info@a-cure.org
August 24, 2023
Hilton Amsterdam
In-person:
Apollolaan 138, 1077 BG
Amsterdam, Netherlands
Virtual: Access link will be provided to registered attendees via email
All meeting times are Central European Time (CET), (GMT+1)
6:30-7:30 a.m.
Breakfast & Check-in
Check-in & Breakfast Location: Nassau & Staten Room
Symposium Location: Balzaar Ball Room
Session I
Advances in the Science of Cardiac Unloading and Myocardial Recovery
8:00-9:40 a.m.
Discussion Leaders: Claudius Mahr, DO (Medical City Heart Hospital, USA) and Dr. Med. L. Christian Napp (Hannover Medical School, Germany)
8:00 a.m.
MC: George Vetrovec, MD (Virginia Commonwealth University, USA)
Welcome and Introductory Comments
8:05-8:15 a.m.
Dan Burkhoff, MD, PhD (Cardiovascular Research Foundation, USA)
The State of the Field of Unloading: Annual Update
8:15-8:30 a.m.
Gaurav Gulati, MD (Tufts Medical Center, USA)
Right Heart Ventriculo-Vascular Coupling in Cardiac Unloading
8:30-8:45 a.m.
Hidetaka Morita, MD (NCVC Osaka, Japan)
Abstract Selected: Automated IMpella Optimized Unloading System (AIMOUS) of Impella 5.5 Precisely Controls Left Ventricular Pressure in Goat
8:45-9:00 a.m.
Rohit Ramchandra, PhD (University of Auckland, New Zealand)
Abstract Selected:Mechanical Circulatory Support using the Impella CP Reduces Directly Recorded Renal Sympathetic Nerve Activity in Cardiogenic Shock
9:00-9:10 a.m.
Open Floor Discussion
9:10-9:40 a.m.
Debate #1
Topic: Unloading and venting VA- ECMO CGS Patients: LAVA or EcPella?
Moderators:
Prof. Dr. Med. Patrick Hunziker (University Hospital Basel, Switzerland) and Nir Uriel, MD (Colmbia University Irving Medical Center, USA)
Debaters:
Bill O’Neill, MD (Henry Ford Hospital, USA) LAVA
Prof. Dr. Med. Dirk Westermann (Universitäts-Herzzentrum Freiburg, Germany) EcPella
Session II
Mechanical Preload Reduction
10:00-11:00 a.m.
Pecha Kucha Format (20 images, each 20 seconds, timed for 7 minutes each)
10:00-10:45 a.m.
Pecha Kucha
Question: Can mechanical preload reduction benefit patients?
Moderators:
Navin Kapur, MD (Tufts Medical Center, USA)
Dan Burkhoff, MD, PhD (Cardiovascular Research Foundation, USA)
Panelists:
Arvind Bhimaraj, MD (Houston Methodist Hospital, USA) Principles of Preload Reduction and Pathophysiology
Manreet Kanwar, MD (Allegheny General Hospital, USA) Acute Decompensated HF and Chronic HF
Rayan Yousefzai, MD (Houston Method Hospital, USA) PreCardia and Renal Unloading
Harrison Farber, MD (Tufts Medical Center, USA) Acute Right Heart Failure and Pulmonary Hypertension
Navin Kapur, MD (Tufts Medical Center, USA) PrePella
10:45-11:00 a.m.
Open Floor Discussion
Live Poster Session
11:00-12:00 p.m.
Diamond Room
12:00-1:00 p.m.
Lunch & Networking
Nassau & Staten Room
Session III
Clinical Evidence and Strategies for Cardiac Unloading and Recovery
1:00-3:00 p.m.
Discussion leaders: Jeff Moses, MD (Columbia University, USA) and Prof. Dr. Med. Jacob Møller (Copenhagen University Hospital, Denmark)
1:00-1:20 p.m.
Ryan Tedford, MD (Medical University South Carolina, USA)
Right Heart Failure: Evaluation and Management
1:20-1:35 p.m.
Allan Böhm, MD (National Cardiovascular Institute, Slovakia)
STOP SHOCK: Artificial Intelligence Model for Prediction of Cardiogenic Shock and MCS use
1:35-1:50 p.m.
Kanika Mody, MD (Hackensack Medical Center, USA)
Abstract Selected:GDMT Optimization in Impella 5.5 Patients
1:50-2:05 p.m.
Debbie Rinde-Hoffman, MD (Tampa General Hospital, USA)
MCS use in High-risk Non-cardiac Surgery, Bariatric Surgery and Beyond
2:05-2:20 p.m.
Thorsten Siess, PhD (Abiomed, GmbH)
The Pediatric Impella Pump
2:20-2:30 p.m.
Open floor Discussion
2:30-3:00 p.m.
Debate #2
Topic: Unloading as a Bridge to Transplant or Target for Recovery: Which Patients and Why?
Moderators:
Mark Anderson, MD (Hackensack Meridian Hospital, USA)
Prof. Dr. Med. Andreas Schäfer (Hannover Medical School, Germany)
Debaters:
Prof. Dr. Med. Alex Bernhardt (University Heart Center Hamburg, Germany) Bridge to Transplant
Jane Wilcox, MD (Northwestern University, USA) Bridge to Recovery
Session IV
Innovations in the Space: Abstract Selected Talks
3:15-5:05 p.m.
Discussion leaders: Prof. Dr. Med. Bart Meyns (KU Leuven, Belgium) and Kiyotake Ishikawa, MD, PhD (Mount Sinai, USA)
3:15-3:40 p.m.
Special Lecture
Kenji Sunagawa, MD, PhD (Kyushu Univ, Japan)
From Past Insights to Future Breakthroughs: Digital Twins to Empower PVR, Circulatory Equilibrium, and MCS
3:40-3:55 p.m.
Best in Research Award
Elric Zweck, MD, PhD (Heinrich-Heine University, Düsseldorf, Germany)
Abstract Selected:Clinical Trajectories and Outcomes in Cardiogenic Shock Phenotypes
3:55-4:10 p.m.
Young Investigator Award
Kimberly Lamberti (MIT, USA)
Abstract Selected:Pulmonary Vascular Dynamics Determines Right Heart Tolerance of Left Ventricular Mechanical Support
4:10-4:25 p.m.
Takaaki Toyofuku, MD (Saiseikai Kumamoto Hospital, Japan)
Abstract Selected:Impact of ECPELLA Support on Intermediate-term Mortality and Myocardial Protection in Patients with Refractory Cardiogenic Shock due to Acute Coronary Syndrome
4:25-4:40 p.m.
Michele Esposito, MD (Medical University of South Carolina, USA)
Abstract Selected:Acute Limb Ischemia Doubles In-Hospital Mortality Among Patients with Cardiogenic Shock: An Analysis from the Cardiogenic Shock Working Group
4:40-4:55 p.m.
Navin Kapur, MD (Tufts Medical Center, USA)*
Abstract Selected:Machine Learning Mortality Prediction for Patients with Cardiogenic Shock due to Acute Decompensated Heart Failure
*On behalf of Song Li, MD (Medical City Heart Hospital, USA)
4:55-5:05 p.m.
Open floor Discussion
5:05 p.m.
Closing Comments, Audience Feedback, and Adjourn
Symposium Survey
5:10-7:00 p.m.
Cocktail Reception & Poster Viewing
Location: Diamond Room
Gallery
Event Photos
Poster Gallery
Shock, It’s a Team Sport: Penn Medicine Shock Team and Community Partnerships Improve Cardiogenic Shock Outcomes
Joyce Wald
A Long Term Relationship: A Review of 107 Patients Supported with Impella 5.5 Device for Extended Durations
Joyce Wald
Prevalence of Advanced Heart Failure in the Obese Population: A Study from the National Inpatient Sample Database
Nicolas Brozzi
Non Cardiac Procedures Under Temporary Mechanical Circulatory Support
Rene Aleman
Mechanical circulatory support aids improved cardiac gener delivery by temporary coronary occlusions
Renata Mazurek
Establishment of the acute Fontan circulation with Impellain a goat model of ventricular fibrillation: a consideration from the point of view of circulatory equilibrium
Shohei Yokota
Accredited Cardiac Arrest Centers Facilitate eCPR and Improve Neurological Outcome
Fabian Voss
Bridge to heart transplantation by an axillary Impella and unloading for primary graft dysfunction after heart transplantation via the same access route– a case report
Constanze Volgmann
Parallel anti-Xa/APTT heparin monitoring during Impella support for cardiogenic shock
Charlotte Van Edom
Serum Lactate Level, Lactate Clearance and One-Year Survival in Cardiac Arrest Patients with Extracorporeal Cardiopulmonary Resuscitation – A multicenter cohort study
Tharusan Thevathasan
Impact of left ventricular ejection fraction on mortality and use of mechanical circulatory support in non-ischaemic cardiogenic shock
Jonas Sundermeyer
Impella support prevents contrast induced acute kidney injury in a highrisk population undergoing percutaneous coronary intervention – Results of the PROTECT Kidney Pilot Trial
Daniel Scheiber
Cardiolipin is a Novel Target of Therapy to Mitigate Myocardial Injury due to Veno-arterial Extracorporeal Membrane Oxygenation (VA-ECMO)
Lara Reyalt
Cardiac non-myocytes and Cell Plasticity play a role in Myocardial Recovery from Heart Failure
Rajul Ranka
Reducing tricuspid gap by 24 hour temporary right ventricular support pump
Anne Palm
Multidisciplinary Team Approach to Reducing Vascular Complications In Impella Supported Patients
Kanika Mody
Native Heart Recovery After Left Ventricular Unloading with the Impella 5.5 in Patients with Cardiogenic Shock
Kanika Mody
Applications of the Impella RP Flex: Single Center Experience
Kanika Mody
Introduction of Guideline Directed Medical Therapy and Native Heart Recovery in Patients Supported by Impella 5.5
Kanika Mody
Axillary Artery Impella 5.5: Single Center Expereince
Kanika Mody
P2Y12 Inhibition in Impella-supported cardiogenic shock
Daniel Metzen
Effects of Mechanical Left Ventricular Unloading on Left Atrial Hemodynamics in Myocardial Infarction
Tomoki Sakata
The Impact of Intra Aortic Balloon Pumping on Impella Supported Hemodynamics
Hiroki Matsushita, MD
Left Ventricular Unloading with Impella Preserves Relaxation and Extends Diastolic Filling Time in Porcine Models of Myocardial Infarction
Jonas Marx, MD
Direct Inhibitory effect of heart failure medications on an in vitro model of endothelial-to mesenchymal transition
Muthu Kumar Krishnamoorthi, MD
Impact of high-profile transvalvular pumps in heart failure – cardiogenic shock
Manreet Kanwar, MD
Comparison of mid-term mortality after surgical, supported or unsupported percutaneous revascularization in patients with severely reduced ejection fraction: a direct and indirect meta-analysis of adjusted observational studies and randomized-controlled
Mario Iannaccone, MD
Characteristics and Outcomes of Combination V A ECMO for Cardiogenic Shock
Jamie Hernandez-Montfort
Hemodynamic contributors to acute kidney injury: A case for combined push and pull failure
Jean Marc Stefan Haurand
Hemodynamic support as an option to improve safety and access to non cardia c surgery procedures in patients with impaired left ventricular function and heart failure
Stefano Guarracini
International variation in frequency, indications and strategies for left ventricular unloading in V-A ECMO
Saad Ezad
Utilization of Impella 5.5 for Escalation and De-escalation of C Shock Care of Patients Transferred to Tampa General Hospital from Community Single Center Experience
Ioana Dumitru
Cardiac Recovery in Cardiomyopathy Cardiogenic Shock Patients Supported with Impella 5.5 Single Center for Experience After Cardiogenic Shock Team Implementation
Ioana Dumitru
Interaction between renal and right ventricular function and their early prognostic relevance in patients with cardiogenic shock complicating AMI
Surnjev Chimed
Myocardial Metabolic Positron Emission Tomography for Viability Assessment During Impella Support
Luca Baldetti
