This report analyzed data on 8910 patients with COVID – 19 from the International Surgical Outcomes Collaborative (Surgisphere) Registry including 169 hospitals located in 11 countries from Asia, Europe and North America. Overall 515 patients died (5.8%) in hospital, while 8395 survived to discharge.
Existing patient characteristics independently associated with in-hospital mortality (shown as % with and without the condition) include:
- Age greater than 65 years (10.0 vs. 4.9%)
- Male sex (6.3 vs. 5.0%)
- Cardiovascular risks
- Coronary Artery Disease (10.2% vs. 5.2%)
- Heart Failure (15.3 vs. 5.6%)
- Cardiac Arrhythmia (11.5 vs. 5.6%)
- COPD (14.2% vs. 5.6%)
- Current Smokers (9.4% vs. 5.6%)
- CV Treatment
- Statins (4.2% on vs. 6% not on – favorable)
- ACE/ARB overall safety (ACE 2.1% on vs. 6.1% not on – favorable; ARB 6.8% on vs. 5.7% off – neutral).
This study reaffirms the significant increased mortality risk for patients with cardiovascular disease or risk factors and importantly, supports prior retrospective reviews regards the safety of ACE/ARB treatment