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Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, and the Northwell COVID-19 Research Consortium. JAMA. doi:10.1001/jama.2020.6775Published online April 22, 2020. Corrected on April 24, 2020.

This report describes COVID – 19 patient outcomes for patients admitted to the Northwell Health System from 12 hospitals including New York City, Long Island and Westchester County, New York March 1 – April 4, 2020. There were 5700 admissions of which 2634 were discharged Alive or died by April 4, with the remainder still hospitalized.

Key Points:

  • Of the 5700 admissions, mean age was 63 yrs. with 61% males consistent with other studies demonstrating a male preponderance of cases.
  • Common comorbidities parallel other reports including hypertension (56.6%), obesity (41.7%), and diabetes (33.8%).
  • Presenting clinical findings included Fever (30.7%), respiratory rate >24/min (17.3%) with supplemental O2 in 27.8%. Respiratory co-infection occurred in 2.1%. Thus, fever is not a predominant finding in hospitalized patients.
  • Of the 2634 patients discharged dead or alive during the study period, 14.2% these patients had ICU admissions (mean age 68 yrs, 66.5 % male). Mechanical ventilation was used in 14.2% of patients (86% of patients admitted to the ICU) with 3.2% requiring renal replacement therapy.
  • Mortality was 21% for the 2634 patients discharged dead or alive by April 4, highly related to having been on mechanical ventilation (88% mortality) and for age >65 years.
  • For patients discharged alive, lymphocyte values tended lower with older age.
  • These data parallel data from other studies re-emphasizing the risk for patients requiring ICU admission and mechanical ventilation, being over age 65 and male.