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Prolonged Impella Mode of Action and Clinical implication

Dr. Tschöpe discusses the use of prolonged Impella support to successfully bridge patients through cardiogenic shock resulting from myocarditis.

  • Dr. Tschope presents clinical and Theoretical concepts regards the potential role of unloading to prevent ventricular remodeling in acute, severe viral myocarditis.
  • The presentation emphasizes the potential effect of unloading may be mediated via reduced inflammatory markers with resultant improvement in cardiac function and associated biopsy evidence of reduced inflammation.
  • While the presentation antedated the Coronavirus Pandemic, the principles may be applicable to a variety of viral etiologies with more experience.