Agenda

August 25, 2016

Time

7:00 pm

A-CURE Cocktail and Dinner Reception

Villa Miani
Via Trionfale 151
00136 Roma, Italy

August 26, 2016

Time

7:30 am – 8:15 am

Breakfast

8:15 am – 8:30 am

Introductory Comments by Conference Chairs

8:30 am – 12:00 am

Session 1

Advances in the Basic Science of Acute Unloading and Myocardial Salvage

Discussion Leaders: Roger Hajjar, Elazer Edelman

8:30 am – 9:15 am

Opening Lecture

Eugene Braunwald

(Harvard School of Medicine)

Acute MI to Heart Failure: The Past, the Present, and the Future

9:15 am – 9:30 am
Discussion

9:30 am – 9:45 am

Dan Burkhoff

The Science Behind Acute Unloading

9:45 am – 9:50 am
Discussion

9:50 am – 10:05 am

Kenji Sunagawa

Neuromodulation and Cardiac Unloading

10:05 am -10:10 am
Discussion

10:10 am – 10:25 am

Navin Kapur

Primary Unloading in AMI and Minimizing Infarct Size

10:25 am – 10:30 am
Discussion

10:30 am – 10:45 am

Break

Discussion Leaders: Andreas Schäfer, Jose Henriques

10:45 am – 11:00 am

Patrick Hunziker

Cardiogenic shock: From Hemodynamic Simulations to Patient Management

11:00 am – 11:05 am
Discussion

11:05 am – 11:20 am

Michele Esposito, Tufts Medical Center, Winner of the Young Investigator Scholarship,

“From Door to Balloon to Door to Unload: A Transcriptomic Analysis Identifies that Primary Unloading Globally Shifts Gene Expression and Preserves Mitochondrial Integrity within the Infarct Zone during the Acute Phase of AMI

11:20 am – 11:25 am
Discussion

11:25 am – 12:00 pm

Panel Discussion #1: Translational research opportunities and challenges

Dan Burkhoff, Kenji Sunagawa, Navin Kapur, Elazer Edelman, Patrick Hunziker

12:00 pm – 1:00 pm

Lunch & Poster Viewing

1:00 pm – 1:45 am

Keynote Speaker

Joseph Hill, MD, PhD

“HEART FAILURE: THE PATH AHEAD”

UT Southwestern

Chief, Division of Cardiology
Editor-In-Chief, Circulation

1:45 am – 2:00 pm
Q & A, Discussion

2:00 pm – 4:30 pm

Session 2

Advances in the Clinical Science of Acute Unloading and Myocardial Salvage

Discussion Leaders: Jacob Møller, Stavros Drakos

2:00 pm – 2:10 pm

Mark Anderson

Unloading the heart is not a new concept: Surgical perspective and clinical utility of acute unloading

2:10 pm – 2:15 pm
Discussion

2:15 pm – 2:25 pm

William O’Neill

Acute unloading in the setting of AMI complicated by Cardiogenic Shock

2:25 pm – 2:30 pm
Discussion

2:30 pm – 2:40 pm

Talk selected from Abstracts, James Udelson, MD, Tufts Medical Center

Incorporating Infarct Size into Trial Composite Endpoints: Implications for Unloading Trials”

2:40 pm – 2:45 pm
Discussion

2:45 pm – 2:55 pm

Takahiro Arimura,  Kyushu University, Winner of the Best In Research Scholarship

“Neuro-Mechanical Unloading for Acute Myocardial Ischemia Synergistically, Strikingly Reduces Infarct Size and Prevents Heart Failure in the Long Term”

2:55 pm – 3:00 pm
Discussion

3:00 pm – 3:15 pm

Break

Discussion Leaders: Nir Uriel, Navin Kapur

3:15 pm – 3:25 pm

Talk Selected From Abstracts, Michael Cohen, University of Southern Alabama

“To Have Clinical Value, Future Cardioprotective Interventions Must Provide Additive Protection to That from a P2Y12 Receptor

3:25 pm – 3:30 pm
Discussion

3:30 pm – 3:40 pm

Ryan Tedford

Mechanical Support for Right-sided and Biventricular Failure

3:40 pm – 3:45 pm
Discussion

3:45 pm – 3:55 pm

Derek Hausenloy

Reducing Myocardial Infarct Size: Translational Challenges and Opportunities

3:55 pm – 4:00 pm
Discussion

4:00 pm – 4:30 pm

Panel Discussion #2: Future Directions of Acute Unloading

Bill O’Neill, Ryan Tedford, Derek Hausenloy, Navin Kapur, Nir Uriel, Eric Peterson, Mark Anderson

4:30 pm – 4:45 pm

Closing comments, audience feedback and adjourn

Dan Burkhoff
Bill O’Neill
Navin Kapur
Mark Anderson

5:00 pm – 7:00 pm

Post-meeting Cocktail Reception & Poster Viewing