The A-CURE Working Group is comprised of leading academic experts in clinical and basic cardiac research that is dedicated to advancing the science and clinical application of acute cardiac unloading.

Featured Resources

Journal of Cardiovascular Transnational Research

In this issue of the Journal of Cardiovascular and Translational Research (JCTR) 10 articles focused on new and emerging topics in the field of mechanical unloading are presented including state-of-the-art reviews and new primary pre-clinical and clinical reports.

Circulation Heart Failure, May 2018

Left Ventricular Mechanical Unloading by Total Support of Impella in Myocardial Infarction Reduces Infarct Size, Preserves Left Ventricular Function, and Prevents Subsequent Heart Failure in Dogs

Transvalvular Ventricular Unloading Before Reperfusion in Acute Myocardial Infarction

Lija Swain, Lara Reyelt, Shreyas Bhave, Xiaoying Qiao, Corinne J. Thomas, Elric Zweck, Paige Crowley, Courtney Boggins, Michele Esposito, Michael Chin, Richard H. Karas, William O’Neil, Navin K. Kapur

View the Latest A-CURE Resources & Publications

Access current publications, abstracts, experimental protocols, and other valuable resources.

Start using the Harvi app today!

Learn cardiovascular physiology, hemodynamics, and pressure-volume loops through this dynamic, interactive simulation.

Have a Question About Acute Cardiac Unloading?

Email the A-CURE Working Group faculty to inquire about the science of unloading, experimental protocols, potential collaborations, or other questions on acute unloading.

Understanding the Pressure-Volume Loop

The pressure-volume loop is an excellent way of understanding the science of acute unloading. This video series presented by Khan Academy provides a first-rate source for educating yourself and your students on the hemodynamic information contained in the P-V loop.