The A-CURE Working Group is comprised of leading academic experts in clinical and basic cardiac research that is dedicated to advancing the science and clinical application of acute cardiac unloading.

Featured Resources

Innovation Lecture: Navin Kapur, MD | Tufts Medical Center

Current Understanding of the Molecular Mechanisms of Unloading & Recovery: Past, Present, and Future – Presented at A-CURE 2022.

Journal of Cardiovascular Transnational Research

In this issue of the Journal of Cardiovascular and Translational Research (JCTR) 10 articles focused on new and emerging topics in the field of mechanical unloading are presented including state-of-the-art reviews and new primary pre-clinical and clinical reports.

Kay Everett, MD, PhD | Tufts Medical Center

Combining VA-ECMO and Impella (EC-Pella) Before Reperfusion Mitigates Left Ventricular Injury Due to VA-ECMO in Acute Myocardial Infarction – Presented at A-CURE 2022

View the Latest A-CURE Resources & Publications

Access current publications, abstracts, experimental protocols, and other valuable resources.

Start using the Harvi app today!

Learn cardiovascular physiology, hemodynamics, and pressure-volume loops through this dynamic, interactive simulation.

Have a Question About Acute Cardiac Unloading?

Email the A-CURE Working Group faculty to inquire about the science of unloading, experimental protocols, potential collaborations, or other questions on acute unloading.

Understanding the Pressure-Volume Loop

The pressure-volume loop is an excellent way of understanding the science of acute unloading. This video series presented by Khan Academy provides a first-rate source for educating yourself and your students on the hemodynamic information contained in the P-V loop.