The Agenda for the 8th Annual A-CURE Symposium will be provided soon. In the meantime, please refer to the previous 7th A-CURE agenda to learn about the exciting research A-CURE is proud to host each year !
November 3, 2022
Chicago Willis Tower
99th Floor, 233 S Wacker Dr.
Chicago, IL 60606
6:00 - 8:00 p.m.
Welcome and Networking Dinner
Pre-conference cocktail reception and dinner with A-CURE faculty and attendees
RSVP only by registration or by emailing info@a-cure.org
November 4, 2022
Chicago Athletic Association Hotel
In-person:
12 S. Michigan Ave
Chicago, IL
Virtual: Access link will be provided to registered attendees via email
All meeting times are Central Daylight Time (UTC-5)
7:00-8:00 a.m.
Breakfast & Check-in
Check-in Location: 8th Floor Lobby
Breakfast Location: White City Ballroom
Symposium: Madison Ballroom
8:00 a.m.
Welcome and Introductory Comments
8:00-8:15 a.m.
Opening Lecture
Dan Burkhoff, MD, PhD (Cardiovascular Research Foundation)
The State of the Field in Cardiac Unloading: Annual Update
Session I
Advances in Basic and Preclinical Science of Acute Unloading and Myocardial Recovery
8:15-9:15 a.m.
Discussion leaders: Kiyotake Ishikawa, MD, PhD (Mt. Sinai) & Patrick Hunziker, MD (Univ. Hospital Basel)
8:15-8:30 a.m.
Bart Meyns, MD, PhD (KU Leuven)
Topic: Reverse Remodeling in an Ovine Model of Ischemic Cardiomyopathy
8:30-8:45 a.m.
Steve Keller, MD, PhD, MPhil (Johns Hopkins Univ.)
Topic: Cardiac State Optimization to Promote Recovery during Extracorporeal Circulatory Support
8:45-9:00 a.m.
Abstract: Peter Frederiksen, MD (Odense Univ. Hospital)
Topic: Cardiac Energetics and Systemic Perfusion with Veno-arterial ECMO versus Ecmella for Cardiogenic Shock in a Large Animal Model
*Presented by Ann Banke, MD, PhD (Odense Univ. Hospital)
9:00-9:15 a.m.
Abstract: Spyros Mavropoulos, MD, PhD (Mt. Sinai)
Topic: An Analysis of Extracellular Matrix Proteins Involved in the Loaded and Unloaded Heart after Myocardial Infarction
Keynote Lecture
9:15-10:00 a.m.
Biykem Bozkurt, MD, PhD
(Editor-in-Chief, JACC: HF; Baylor College of Medicine)
Topic: Decompensated Heart Failure, Taking the Acute out of Decompensation
Introduction: Bobbi Bogaev Chapman, MD
10:00-10:15 a.m.
Break
Session II
Clinical Science and Evidence for Cardiac Unloading & Recovery
10:15-11:30 a.m.
Discussion leaders: Claudius Mahr, DO (Univ.of Washington) & Jacob Møller, MD (Odense Univ. Hospital)
10:15-10:30 a.m.
William O’Neill, MD (Henry Ford Hospital)
Topic: Impact of CMR-derived Infarct Size on LV Remodeling: the Roll-in DTU Experience
10:30-10:45 a.m.
Navin Kapur, MD (Tufts Medical Center)
Topic: Delaying Reperfusion for Thirty Minutes in the Presence of Active LV Unloading Reduces Infarct Size in Anterior STEMI: A Per Protocol Analysis of the STEMI Door to Unload (DTU) Pilot Study
10:45-11:00 a.m.
Ralf Westenfeld, MD (Univ. Düsseldorf)
Topic: PROTECT Kidney Randomized Controlled Trial – MRI Pilot Study
11:00-11:15 a.m.
Paul Haller, MD (UKE Hamburg)
Topic: Automatic LV Unloading using a Percutaneous Transvalvular Microaxial Flow Pump during VA-ECMO Support
*Presented by: Benedikt Schrage, MD (UKE Hamburg)
11:15-11:30 a.m.
Christian Moyer, PhD (Abiomed, Inc)
Topic: Smarter Pumps: Measuring Cardiac Function with Impella Signals
11:30-11:45 a.m.
Break
Session III
Emerging Trials In Clinical Applications of Cardiac Unloading
11:45-12:30 p.m.
Discussion leaders: Andreas Schäfer, MD (Hannover Medical Center) and Carsten Tschöpe, MD (Charité – Univ. Berlin)
11:45-12:00 p.m.
Benedikt Schrage, MD (UKE Hamburg)
Topic: Unload-ECMO Randomized Controlled Trial for LV Unloading with VA-ECMO in Severe Cardiogenic Shock
12:00-12:15 p.m.
Mir Babar Basir, DO (Henry Ford Hospital)
Topic: CERAMICS: Best Practices for MCS Escalation and Management in AMI-CS
12:15-12:30 p.m.
Alex Nap, MD, PharmD, PhD (UMC Amsterdam)
Topic: UNLOAD-HF Randomized Controlled Trial for LV Unloading in Acute Heart Failure
Live Poster Session
12:30-2:00 p.m.
Location: White City Ballroom
Lunch will be served
Awards Announcements: Navin Kapur, MD (Tufts Medical Center) and Kenji Sunagawa, MD, PhD (Kyushu University)
2:00-2:15 p.m.
Young Investigator Award
Lija Swain, PhD (Tufts Medical Center)
Topic: Trans-Valvular Unloading Reduces Anaerobic Glycolysis before Reperfusion and Preserves Energy Substrate Utilization after Reperfusion in Models of Acute Myocardial Infarction
2:15-2:30 p.m.
Best in Research Award
Tomoki Sakata, MD, PhD (Mt. Sinai)
Topic: Mechanical LV Unloading Increases Coronary Flow by Prolonging Diastolic Phase
2:30-2:55 p.m.
Panel Discussion
Topic: Targeting Heart Recovery in a Real-World Setting
Panelists:
Manreet Kanwar, MD (Allegheny General Hospital)
Jane Wilcox, MD (Northwestern Medicine)
Bart Meyns, PhD (UZ Leuven)
Moderator:
Bobbi Bogaev Chapman, MD
2:55-3:15 p.m.
Break
Session IV
Frontiers in Surgical and Clinical Applications of Unloading
3:15-5:00 p.m.
Discussion leader: Mark Anderson, MD (Hackensack Meridian)
3:15-3:30 p.m.
Abstract: Alessandro Beneduce, MD (IRCCS San Raffaele)
Topic: A Novel Fluoroscopic Approach to Impella Percutaneous Ventricular Assist Device Positioning
*Presented by Luca Baldetti, MD, (IRCCS San Raffaele)
3:30-3:45 p.m.
Abstract: Kay Everett, MD, PhD (Tufts Medical Center)
Topic: Left Ventricular Unloading Acutely Reduces Right Ventricular Preload in Patients with Acute Decompensated Heart Failure and Cardiogenic Shock
3:45-4:00 p.m.
Ryan Tedford, MD (Medical College of South Carolina)
Topic: The Role of RV Reserve Assessment and LV Unloading to Predict Right Heart Failure after LVAD Implantation
4:00-4:25 p.m.
Panel Discussion
Topic: Advanced Surgical Uses of PVAD Support and Patient Management
Moderator:
Mark Anderson, MD (Hackensack Meridian Health)
Brief case presentation:
Hermann Reichenspurner, MD (UKE Hamburg)
Alexander Bernhardt, MD (UKE Hamburg)
Panelists:
Hermann Reichenspurner, MD, PhD (UKE Hamburg)
Alexander Bernhardt, MD (UKE Hamburg)
4:25-4:55 p.m.
Panel Discussion
Topic: Non-Cardiac Surgery Interventions on Patients Receiving Impella Support
Panelists:
Nicolas Brozzi, MD (Cleveland Clinic Florida)
Raul Rosenthal, MD (Cleveland Clinic Florida)
Jaime Hernandez-Montfort, MD (Baylor Scott & White Health)
Ramachandra Reddy, MD (Baylor Scott & White Health)
Modesto J. Colón, MD (Banner Univ. Medical Center)
Radha S. Gopalan, MD (Banner Univ. Medical Center)
4:55-5:00 p.m.
Session Closing
5:00 p.m.
Closing Comments, Audience Feedback, and Adjourn
Topics: How to Claim CME Credit / Evaluation Form
5:00-7:00 p.m.
Cocktail Reception & Poster Viewing
Location: White City Ballroom
Note: Topics and session time may update.